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In the ancient moments, the shamans of the indigenous western Amazonian tribes generally took the plant as purgative and/or antiparasitic during the spiritual and therapeutic ceremonies, even though presently It's a sacred beverage of some religious communities in Brazil and North America (Santo Daime) [7].
It's been observed the Affiliation of mescaline and various medicine can result in dependence and tolerance (described as the reduction from the Organic response to a relentless dose of Energetic ingredient) [110]; as an example a crossed tolerance could be induced by the idea of mescaline with other hallucinogens for instance LSD and psilocybin [111]. This tolerance can speedily minimize, within several times of halting the drug.
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